Peyronie's Disease

Peyronie’s disease is when a male’s penis has an abnormal curvature during erection. Up to 7 percent of males experience Peyronie’s disease, and it is typically caused by penile trauma during sexual intercourse.Any injury to the tunica albuginea may result in scar tissue forming in the cells, which forms the plaque of Peyronie's Disease. 

Signs that you have Peyronie's Disease are:Peyronie's

  • Bent / curved penis
  • Lumps on the penis
  • Painful erections
  • Soft erections

Peyronie's Disease is usually split into the acute and chronic phases. The acute phase is the first 6 to 18 months. During this time the plaque forms in the penis, and the curving of the penis continues to get worse. The chronic phase is when the plaque stops growing and then penis does not continue to curve. 


The goal of treatment is to reduce pain and keep you sexually active. There is no cure. Education about the disease and its usual course is often included in the treatment plan. In some cases, treatment is not needed. Peyronie disease often happens in a mild form that heals on its own in 6 to 15 months. Treatment may include:

  • Vitamin E. Small studies have reported improvements with oral vitamin E, but larger studies have not been done to prove that this treatment works. Still, this is an easy, low cost treatment choice.
  • Various medicines. Many medicines taken by mouth have been tried, but none are proven to work in all men. If your healthcare provider wants to try medicine, be sure you understand what it is, what’s known about it, and what side effects you should watch for.
  • Xiaflex®. is a prescription medicine that is injected into the scar tissue to weaken and break down the plaque.
  • Surgery may be used to correct the plaque in severe cases, such as when the man has pain during an erection or can’t keep an erection long enough to have sex.
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